Acute eosinophilic pneumonia (AEP) is one of the causes of acute respiratory failure. Classical clinical picture includes acute febrile illness, bilateral pulmonary opacities, pulmonary eosinophilia, hypoxia, and pleuritic chest pain. We observed AEP with atypical presentation after recent waterpipe (hookah) smoking in our patient. We reported the case of a male with laboratory AEP findings without the typical clinical presentation which resolved after abstinence from waterpipe smoking.